@biothings-explorer/query_graph_handler
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1.18.0 • Public • Published

BioThings Explorer TRAPI Query Graph Handler

A on-the-fly query engine for BioThings Explorer based on TRAPI Query Graph.

Test Coveralls Coverage Status

Install

npm i @biothings-explorer/query_graph_handler

Usage

Making a single hop query

const handler = require("@biothings-explorer/query_graph_handler");
const queryHandler = new handler.TRAPIQueryHandler();
const oneHopQuery = {
    "workflow": [
        {"id": "lookup"}
    ],
    "message": {
        "query_graph": {
            "edges": {
                "e00": {
                    "object": "n01",
                    "subject": "n00",
                    "predicates": ["biolink:functional_association"]
                }
            },
            "nodes": {
                "n00": {
                    "categories": ["biolink:Gene"],
                    "ids": ["ENSEMBL:ENSG00000123374"]
                },
                "n01": {
                    "categories": ["biolink:BiologicalProcess"]
                }
            }
        }
    }
};
queryHandler.setQueryGraph(OneHopQuery);
await queryHandler.query();
console.log(queryHandler.getResponse())
Example Result
{
    "workflow": [
        {"id": "lookup"}
    ],
    "message": {
        "query_graph": {
            "edges": {
                "e00": {
                    "object": "n01",
                    "subject": "n00",
                    "predicate": "biolink:enables"
                }
            },
            "nodes": {
                "n00": {
                    "category": "biolink:Gene",
                    "id": "ENSEMBL:ENSG00000123374"
                },
                "n01": {
                    "category": "biolink:BiologicalProcess"
                }
            }
        },
        "knowledge_graph": {
            "nodes": {
                "NCBIGene:1017": {
                    "category": "biolink:Gene",
                    "name": "CDK2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:1017",
                                "name:cyclin dependent kinase 2",
                                "SYMBOL:CDK2",
                                "UMLS:C1332733",
                                "UMLS:C0108855",
                                "HGNC:1771",
                                "UniProtKB:P24941",
                                "ENSEMBL:ENSG00000123374",
                                "OMIM:116953"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0000082": {
                    "category": "biolink:BiologicalProcess",
                    "name": "G1/S transition of mitotic cell cycle",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0000082",
                                "name:G1/S transition of mitotic cell cycle"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0000086": {
                    "category": "biolink:BiologicalProcess",
                    "name": "G2/M transition of mitotic cell cycle",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0000086",
                                "name:G2/M transition of mitotic cell cycle"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0006260": {
                    "category": "biolink:BiologicalProcess",
                    "name": "DNA replication",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0006260",
                                "name:DNA replication"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0006281": {
                    "category": "biolink:BiologicalProcess",
                    "name": "DNA repair",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0006281",
                                "name:DNA repair"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0006468": {
                    "category": "biolink:BiologicalProcess",
                    "name": "protein phosphorylation",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0006468",
                                "name:protein phosphorylation"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0006977": {
                    "category": "biolink:BiologicalProcess",
                    "name": "DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0006977",
                                "name:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0007099": {
                    "category": "biolink:BiologicalProcess",
                    "name": "centriole replication",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0007099",
                                "name:centriole replication"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0007165": {
                    "category": "biolink:BiologicalProcess",
                    "name": "signal transduction",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0007165",
                                "name:signal transduction"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0007265": {
                    "category": "biolink:BiologicalProcess",
                    "name": "Ras protein signal transduction",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0007265",
                                "name:Ras protein signal transduction"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0008284": {
                    "category": "biolink:BiologicalProcess",
                    "name": "positive regulation of cell population proliferation",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0008284",
                                "name:positive regulation of cell population proliferation"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0010389": {
                    "category": "biolink:BiologicalProcess",
                    "name": "regulation of G2/M transition of mitotic cell cycle",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0010389",
                                "name:regulation of G2/M transition of mitotic cell cycle"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0010468": {
                    "category": "biolink:BiologicalProcess",
                    "name": "regulation of gene expression",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0010468",
                                "name:regulation of gene expression"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0016572": {
                    "category": "biolink:BiologicalProcess",
                    "name": "histone phosphorylation",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0016572",
                                "name:histone phosphorylation"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0018105": {
                    "category": "biolink:BiologicalProcess",
                    "name": "peptidyl-serine phosphorylation",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0018105",
                                "name:peptidyl-serine phosphorylation"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0031145": {
                    "category": "biolink:BiologicalProcess",
                    "name": "anaphase-promoting complex-dependent catabolic process",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0031145",
                                "name:anaphase-promoting complex-dependent catabolic process"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0031571": {
                    "category": "biolink:BiologicalProcess",
                    "name": "mitotic G1 DNA damage checkpoint",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0031571",
                                "name:mitotic G1 DNA damage checkpoint"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0051298": {
                    "category": "biolink:BiologicalProcess",
                    "name": "centrosome duplication",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0051298",
                                "name:centrosome duplication"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0051301": {
                    "category": "biolink:BiologicalProcess",
                    "name": "cell division",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0051301",
                                "name:cell division"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0051321": {
                    "category": "biolink:BiologicalProcess",
                    "name": "meiotic cell cycle",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0051321",
                                "name:meiotic cell cycle"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0060968": {
                    "category": "biolink:BiologicalProcess",
                    "name": "regulation of gene silencing",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0060968",
                                "name:regulation of gene silencing"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:0071732": {
                    "category": "biolink:BiologicalProcess",
                    "name": "cellular response to nitric oxide",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:0071732",
                                "name:cellular response to nitric oxide"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "GO:1901796": {
                    "category": "biolink:BiologicalProcess",
                    "name": "regulation of signal transduction by p53 class mediator",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "GO:1901796",
                                "name:regulation of signal transduction by p53 class mediator"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                }
            },
            "edges": {
                "NCBIGene:1017-GO:0000082-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0000082",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IBA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "G1/S transition of mitotic cell cycle",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:21873635"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0000086-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0000086",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "NAS",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "G2/M transition of mitotic cell cycle",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:1653904"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0006260-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0006260",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "TAS",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "DNA replication",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:19238148"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0006281-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0006281",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IEA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "DNA repair",
                            "type": "bts:term"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0006468-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0006468",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IBA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "protein phosphorylation",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:21873635"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0006977-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0006977",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "TAS",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",
                            "type": "bts:term"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0007099-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0007099",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IMP",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "centriole replication",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:26297806"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0007165-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0007165",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IBA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "signal transduction",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:21873635"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0007265-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0007265",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IEP",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "Ras protein signal transduction",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:9054499"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0008284-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0008284",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IBA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "positive regulation of cell population proliferation",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:21873635"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0010389-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0010389",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IBA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "regulation of G2/M transition of mitotic cell cycle",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:21873635"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0010468-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0010468",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IBA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "regulation of gene expression",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:21873635"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0016572-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0016572",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IDA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "histone phosphorylation",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:11746698"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0018105-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0018105",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IDA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "peptidyl-serine phosphorylation",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:23184662"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0031145-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0031145",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "TAS",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "anaphase-promoting complex-dependent catabolic process",
                            "type": "bts:term"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0031571-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0031571",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "TAS",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "mitotic G1 DNA damage checkpoint",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:21319273"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0051298-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0051298",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "TAS",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "centrosome duplication",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:19238148"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0051301-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0051301",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IEA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "cell division",
                            "type": "bts:term"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0051321-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0051321",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "TAS",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "meiotic cell cycle",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:19238148"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0060968-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0060968",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "IDA",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "regulation of gene silencing",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:20935635"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:0071732-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:0071732",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "TAS",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "cellular response to nitric oxide",
                            "type": "bts:term"
                        },
                        {
                            "name": "publications",
                            "value": [
                                "PMID:20079829"
                            ],
                            "type": "biolink:publications"
                        }
                    ]
                },
                "NCBIGene:1017-GO:1901796-MyGene.info API-entrez": {
                    "predicate": "biolink:enables",
                    "subject": "NCBIGene:1017",
                    "object": "GO:1901796",
                    "attributes": [
                        {
                            "name": "provided_by",
                            "value": "entrez",
                            "type": "biolink:provided_by"
                        },
                        {
                            "name": "api",
                            "value": "MyGene.info API",
                            "type": "bts:api"
                        },
                        {
                            "name": "evidence",
                            "value": "TAS",
                            "type": "bts:evidence"
                        },
                        {
                            "name": "term",
                            "value": "regulation of signal transduction by p53 class mediator",
                            "type": "bts:term"
                        }
                    ]
                }
            }
        },
        "results": [
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0000082"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0000082-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0000082"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0000082-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0000086"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0000086-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0000086"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0000086-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0006260"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0006260-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0006281"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0006281-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0006468"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0006468-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0006468"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0006468-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0006468"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0006468-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0006977"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0006977-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0007099"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0007099-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0007165"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0007165-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0007265"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0007265-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0008284"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0008284-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0008284"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0008284-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0010389"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0010389-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0010468"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0010468-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0016572"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0016572-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0018105"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0018105-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0031145"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0031145-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0031571"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0031571-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0051298"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0051298-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0051301"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0051301-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0051321"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0051321-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0060968"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0060968-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:0071732"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:0071732-MyGene.info API-entrez"
                        }
                    ]
                }
            },
            {
                "node_bindings": {
                    "n00": [
                        {
                            "id": "NCBIGene:1017"
                        }
                    ],
                    "n01": [
                        {
                            "id": "GO:1901796"
                        }
                    ]
                },
                "edge_bindings": {
                    "e00": [
                        {
                            "id": "NCBIGene:1017-GO:1901796-MyGene.info API-entrez"
                        }
                    ]
                }
            }
        ]
    },
    "logs": [
        {
            "timestamp": "2021-03-15T22:48:10.757Z",
            "level": "DEBUG",
            "message": "BTE identified 2 QNodes from your query graph",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.757Z",
            "level": "DEBUG",
            "message": "BTE identified 1 QEdges from your query graph",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.757Z",
            "level": "DEBUG",
            "message": "BTE identified your query graph as a 1-depth query graph",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.757Z",
            "level": "DEBUG",
            "message": "REDIS cache is not enabled.",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.797Z",
            "level": "DEBUG",
            "message": "BTE found 1 smartapi edges corresponding to e00. These smartaip edges comes from 1 unique APIs. They are MyGene.info API",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.808Z",
            "level": "DEBUG",
            "message": "BTE found 1 bte edges for this batch.",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.808Z",
            "level": "DEBUG",
            "message": "call-apis: Resolving ID feature is turned on",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.808Z",
            "level": "DEBUG",
            "message": "call-apis: Number of BTE Edges received is 1",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.828Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://mygene.info/v3/query\",\"params\":{\"fields\":\"go.BP\"},\"data\":\"q=1017&scopes=entrezgene\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.839Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 27 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.839Z",
            "level": "DEBUG",
            "message": "call-apis: Total number of results returned for this query is 27",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:48:10.857Z",
            "level": "DEBUG",
            "message": "call-apis: Query completes",
            "code": null
        }
    ]
}

Making a multi hop query

const handler = require("@biothings-explorer/query_graph_handler");
const queryHandler = new handler.TRAPIQueryHandler();
const multiHopQuery = {
    "workflow": [
        {"id": "lookup"}
    ],
    "message": {
        "query_graph": {
            "nodes": {
                "n0": {
                    "categories": ["biolink:Disease"],
                    "ids": ["MONDO:0005737"]
                },
                "n1": {
                    "categories": ["biolink:Gene"]
                },
                "n2": {
                    "categories": ["biolink:SmallMolecule"]
                }
            },
            "edges": {
                "e01": {
                    "subject": "n0",
                    "object": "n1"
                },
                "e02": {
                    "subject": "n1",
                    "object": "n2"
                }
            }
        }
    }
}
queryHandler.setQueryGraph(multiHopQuery);
await queryHandler.query();
console.log(queryHandler.getResponse())
Example Result
{
    "workflow": [
        {"id": "lookup"}
    ],
    "message": {
        "query_graph": {
            "nodes": {
                "n0": {
                    "category": "biolink:Disease",
                    "id": "MONDO:0005737"
                },
                "n1": {
                    "category": "biolink:Gene"
                },
                "n2": {
                    "category": "biolink:ChemicalSubstance"
                }
            },
            "edges": {
                "e01": {
                    "subject": "n0",
                    "object": "n1"
                },
                "e02": {
                    "subject": "n1",
                    "object": "n2"
                }
            }
        },
        "knowledge_graph": {
            "nodes": {
                "MONDO:0005737": {
                    "category": "biolink:Disease",
                    "name": "Ebola hemorrhagic fever",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "MONDO:0005737",
                                "DOID:4325",
                                "UMLS:C0282687",
                                "name:Ebola hemorrhagic fever",
                                "MESH:D019142",
                                "EFO:0007243",
                                "ORPHANET:319218",
                                "GARD:2035"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:116534309": {
                    "category": "biolink:Gene",
                    "name": "CD4",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:116534309",
                                "name:CD4 molecule",
                                "SYMBOL:CD4"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:539109": {
                    "category": "biolink:Gene",
                    "name": "MMP11",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:539109",
                                "name:matrix metallopeptidase 11",
                                "SYMBOL:MMP11",
                                "ENSEMBL:ENSBTAG00000006108"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:102448557": {
                    "category": "biolink:Gene",
                    "name": "GTPBP1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:102448557",
                                "name:GTP binding protein 1",
                                "SYMBOL:GTPBP1",
                                "ENSEMBL:ENSPSIG00000004300"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:103074707": {
                    "category": "biolink:Gene",
                    "name": "CCL2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:103074707",
                                "name:C-C motif chemokine ligand 2",
                                "SYMBOL:CCL2"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:ENSSPUG00000015633": {
                    "category": "biolink:Gene",
                    "name": "MAPRE3",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:microtubule associated protein RP/EB family member 3",
                                "SYMBOL:MAPRE3",
                                "ENSEMBL:ENSSPUG00000015633"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:115865406": {
                    "category": "biolink:Gene",
                    "name": "BST2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:115865406",
                                "name:bone marrow stromal cell antigen 2",
                                "SYMBOL:BST2"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:110132571": {
                    "category": "biolink:Gene",
                    "name": "IL1B",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:110132571",
                                "name:interleukin 1 beta",
                                "SYMBOL:IL1B"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101571570": {
                    "category": "biolink:Gene",
                    "name": "Ifih1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101571570",
                                "name:interferon induced with helicase C domain 1",
                                "SYMBOL:Ifih1",
                                "ENSEMBL:ENSODEG00000013586"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:ENSSMAG00000017984": {
                    "category": "biolink:Gene",
                    "name": "npc1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:Niemann-Pick disease, type C1",
                                "SYMBOL:npc1",
                                "ENSEMBL:ENSSMAG00000017984"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:397686": {
                    "category": "biolink:Gene",
                    "name": "IFNA1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:397686",
                                "name:interferon, alpha 1",
                                "SYMBOL:IFNA1",
                                "ENSEMBL:ENSSSCG00000050619"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:102892030": {
                    "category": "biolink:Gene",
                    "name": "ALB",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:102892030",
                                "name:albumin",
                                "SYMBOL:ALB"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:104045425": {
                    "category": "biolink:Gene",
                    "name": "HDX",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:104045425",
                                "name:highly divergent homeobox",
                                "SYMBOL:HDX"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:110137949": {
                    "category": "biolink:Gene",
                    "name": "CXCL10",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:110137949",
                                "name:C-X-C motif chemokine ligand 10",
                                "SYMBOL:CXCL10"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:105822820": {
                    "category": "biolink:Gene",
                    "name": "CXCL8",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:105822820",
                                "name:C-X-C motif chemokine ligand 8",
                                "SYMBOL:CXCL8",
                                "ENSEMBL:ENSPCOG00000024593"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:116479423": {
                    "category": "biolink:Gene",
                    "name": "CLEC4M",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:116479423",
                                "name:C-type lectin domain family 4 member M",
                                "SYMBOL:CLEC4M"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:103814882": {
                    "category": "biolink:Gene",
                    "name": "F3",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:103814882",
                                "name:coagulation factor III, tissue factor",
                                "SYMBOL:F3",
                                "ENSEMBL:ENSSCAG00000012591"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101142722": {
                    "category": "biolink:Gene",
                    "name": "KPNA1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101142722",
                                "name:karyopherin subunit alpha 1",
                                "SYMBOL:KPNA1"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:104673720": {
                    "category": "biolink:Gene",
                    "name": "CTSL",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:104673720",
                                "name:cathepsin L",
                                "SYMBOL:CTSL",
                                "ENSEMBL:ENSRROG00000038398"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:116543050": {
                    "category": "biolink:Gene",
                    "name": "CTSB",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:116543050",
                                "name:cathepsin B",
                                "SYMBOL:CTSB"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:29798": {
                    "category": "biolink:Gene",
                    "name": "C2orf27A",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:29798",
                                "name:chromosome 2 open reading frame 27A",
                                "SYMBOL:C2orf27A",
                                "UMLS:C2681192",
                                "HGNC:25077",
                                "UniProtKB:P0DPF5"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:118012204": {
                    "category": "biolink:Gene",
                    "name": "STAT1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:118012204",
                                "name:signal transducer and activator of transcription 1",
                                "SYMBOL:STAT1"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:103531663": {
                    "category": "biolink:Gene",
                    "name": "KPNA5",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:103531663",
                                "name:karyopherin subunit alpha 5",
                                "SYMBOL:KPNA5"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:ENSNVIG00000024389": {
                    "category": "biolink:Gene",
                    "name": "IFIT2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:interferon induced protein with tetratricopeptide repeats 2",
                                "SYMBOL:IFIT2",
                                "ENSEMBL:ENSNVIG00000024389"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:104395366": {
                    "category": "biolink:Gene",
                    "name": "THBD",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:104395366",
                                "name:thrombomodulin",
                                "SYMBOL:THBD"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:100731608": {
                    "category": "biolink:Gene",
                    "name": "Isg15",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:100731608",
                                "name:ISG15 ubiquitin like modifier",
                                "SYMBOL:Isg15"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:108529797": {
                    "category": "biolink:Gene",
                    "name": "DDX58",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:108529797",
                                "name:DExD/H-box helicase 58",
                                "SYMBOL:DDX58",
                                "ENSEMBL:ENSRBIG00000040257"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:106971145": {
                    "category": "biolink:Gene",
                    "name": "IFNB1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:106971145",
                                "name:interferon beta 1",
                                "SYMBOL:IFNB1"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "SYMBOL:GP2": {
                    "category": "biolink:Gene",
                    "name": "GP2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:Polygalacturonase non-catalytic subunit AroGP2",
                                "SYMBOL:GP2"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101443464": {
                    "category": "biolink:Gene",
                    "name": "GPT",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101443464",
                                "name:glutamic--pyruvic transaminase",
                                "SYMBOL:GPT"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:102387082": {
                    "category": "biolink:Gene",
                    "name": "IRF7",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:102387082",
                                "name:interferon regulatory factor 7",
                                "SYMBOL:IRF7"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:109055884": {
                    "category": "biolink:Gene",
                    "name": "il6",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:109055884",
                                "name:interleukin 6 (interferon, beta 2)",
                                "SYMBOL:il6",
                                "ENSEMBL:ENSCCRG00000034667"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:ENSSBOG00000011322": {
                    "category": "biolink:Gene",
                    "name": "CD8A",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:CD8a molecule",
                                "SYMBOL:CD8A",
                                "ENSEMBL:ENSSBOG00000011322"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:117759282": {
                    "category": "biolink:Gene",
                    "name": "ace2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:117759282",
                                "name:angiotensin I converting enzyme 2",
                                "SYMBOL:ace2"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:103562469": {
                    "category": "biolink:Gene",
                    "name": "TNF",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:103562469",
                                "name:tumor necrosis factor",
                                "SYMBOL:TNF"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:112648300": {
                    "category": "biolink:Gene",
                    "name": "IL10",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:112648300",
                                "name:interleukin 10",
                                "SYMBOL:IL10",
                                "ENSEMBL:ENSCAFG00020012434"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:105221759": {
                    "category": "biolink:Gene",
                    "name": "ERVW-1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:105221759",
                                "name:endogenous retrovirus group W member 1, envelope",
                                "SYMBOL:ERVW-1"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:118335909": {
                    "category": "biolink:Gene",
                    "name": "irf3",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:118335909",
                                "name:interferon regulatory factor 3",
                                "SYMBOL:irf3"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101674197": {
                    "category": "biolink:Gene",
                    "name": "CCL5",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101674197",
                                "name:C-C motif chemokine ligand 5",
                                "SYMBOL:CCL5"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:103089296": {
                    "category": "biolink:Gene",
                    "name": "CCL3",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:103089296",
                                "name:C-C motif chemokine ligand 3",
                                "SYMBOL:CCL3"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:100136221": {
                    "category": "biolink:Gene",
                    "name": "ccl4",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:100136221",
                                "name:CCL4 protein",
                                "SYMBOL:ccl4",
                                "ENSEMBL:ENSOMYG00000026069"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:118023076": {
                    "category": "biolink:Gene",
                    "name": "FURIN",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:118023076",
                                "name:furin, paired basic amino acid cleaving enzyme",
                                "SYMBOL:FURIN"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:574217": {
                    "category": "biolink:Gene",
                    "name": "CCL4L1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:574217",
                                "name:chemokine (C-C motif) ligand 4-like 1",
                                "SYMBOL:CCL4L1",
                                "UniProtKB:Q8HYQ2",
                                "ENSEMBL:ENSMMUG00000020102"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1707151": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1707151",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1707151"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1707163": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1707163",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1707163"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:3601": {
                    "category": "biolink:Gene",
                    "name": "IL15RA",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:3601",
                                "name:interleukin 15 receptor subunit alpha",
                                "SYMBOL:IL15RA",
                                "UMLS:C1416387",
                                "HGNC:5978",
                                "UniProtKB:Q13261",
                                "ENSEMBL:ENSG00000134470",
                                "OMIM:601070"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:5788": {
                    "category": "biolink:Gene",
                    "name": "PTPRC",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:5788",
                                "name:protein tyrosine phosphatase receptor type C",
                                "SYMBOL:PTPRC",
                                "UMLS:C1335285",
                                "HGNC:9666",
                                "UniProtKB:P08575",
                                "ENSEMBL:ENSG00000081237",
                                "ENSEMBL:ENSG00000262418",
                                "OMIM:151460"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:8030": {
                    "category": "biolink:Gene",
                    "name": "CCDC6",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:8030",
                                "name:coiled-coil domain containing 6",
                                "SYMBOL:CCDC6",
                                "UMLS:C1425774",
                                "HGNC:18782",
                                "UniProtKB:Q16204",
                                "ENSEMBL:ENSG00000108091",
                                "OMIM:601985"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:920": {
                    "category": "biolink:Gene",
                    "name": "CD4",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:920",
                                "name:CD4 molecule",
                                "SYMBOL:CD4",
                                "UMLS:C1332714",
                                "HGNC:1678",
                                "UniProtKB:P01730",
                                "ENSEMBL:ENSG00000010610",
                                "OMIM:186940"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:1514": {
                    "category": "biolink:Gene",
                    "name": "CTSL",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:1514",
                                "name:cathepsin L",
                                "SYMBOL:CTSL",
                                "UMLS:C1332807",
                                "UMLS:C0054871",
                                "HGNC:2537",
                                "UniProtKB:P07711",
                                "ENSEMBL:ENSG00000135047",
                                "OMIM:116880"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1706438": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1706438",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1706438"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1367471": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1367471",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1367471"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:3439": {
                    "category": "biolink:Gene",
                    "name": "IFNA1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:3439",
                                "name:interferon alpha 1",
                                "SYMBOL:IFNA1",
                                "UMLS:C1415900",
                                "HGNC:5417",
                                "UniProtKB:P01562",
                                "ENSEMBL:ENSG00000197919",
                                "OMIM:147660"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1708411": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1708411",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1708411"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C0017337": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C0017337",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C0017337"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1335439": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1335439",
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    "logs": [
        {
            "timestamp": "2021-03-15T22:54:01.080Z",
            "level": "DEBUG",
            "message": "BTE identified 3 QNodes from your query graph",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.080Z",
            "level": "DEBUG",
            "message": "BTE identified 2 QEdges from your query graph",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.080Z",
            "level": "DEBUG",
            "message": "BTE identified your query graph as a 2-depth query graph",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.080Z",
            "level": "DEBUG",
            "message": "REDIS cache is not enabled.",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.160Z",
            "level": "DEBUG",
            "message": "BTE found 23 smartapi edges corresponding to e01. These smartaip edges comes from 7 unique APIs. They are MyDisease.info API,MGIgene2phenotype API,DISEASES API,SEMMED Disease API,Text Mining CO-OCCURRENCE API,TCGA Mutation Frequency KP API,BioLink API",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.297Z",
            "level": "DEBUG",
            "message": "BTE found 23 bte edges for this batch.",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.297Z",
            "level": "DEBUG",
            "message": "call-apis: Resolving ID feature is turned on",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.297Z",
            "level": "DEBUG",
            "message": "call-apis: Number of BTE Edges received is 23",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.321Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"http://mydisease.info/v1/query\",\"params\":{\"fields\":\"disgenet.genes_related_to_disease\"},\"data\":\"q=C0282687&scopes=mondo.xrefs.umls, disgenet.xrefs.umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.325Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.388Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/DISEASES/query\",\"params\":{\"fields\":\"DISEASES.associatedWith\"},\"data\":\"q=DOID:4325&scopes=DISEASES.doid\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.397Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 42 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.398Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/text_mining_co_occurrence_kp/query\",\"params\":{\"fields\":\"subject,association\",\"q\":\"object.MONDO:\\\"MONDO:0005737\\\" AND subject.type:Gene\",\"size\":1000},\"method\":\"get\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.398Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.398Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/mgigene2phenotype/query\",\"params\":{\"fields\":\"_id\",\"size\":\"300\"},\"data\":\"q=DOID:4325&scopes=mgi.associated_with_disease.doid\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.398Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.399Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/tcga_mut_freq_kp/query\",\"params\":{\"fields\":\"association.freq_by_sample,subject.SYMBOL\",\"q\":\"object.id:\\\"MONDO:0005737\\\" AND association.freq_by_sample:>0.1\",\"size\":\"1000\",\"sort\":\"-association.freq_by_sample\"},\"method\":\"get\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.399Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.399Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"caused_by\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.400Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 2 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.400Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"affected_by\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.400Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 7 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.401Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"affects\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.401Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.439Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/text_mining_co_occurrence_kp/query\",\"params\":{\"fields\":\"object,association\",\"q\":\"subject.MONDO:\\\"MONDO:0005737\\\" AND object.type:Gene\",\"size\":1000},\"method\":\"get\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.628Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.706Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://api.monarchinitiative.org/api/bioentity/disease/MONDO:0005737/genes\",\"params\":{\"direct\":true,\"rows\":200,\"unselect_evidence\":true},\"method\":\"get\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.707Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.709Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://api.monarchinitiative.org/api/bioentity/disease/MONDO:0005737/genes\",\"params\":{\"direct\":true,\"rows\":200,\"unselect_evidence\":true},\"method\":\"get\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.709Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.722Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"derives_from\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.722Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.723Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"disrupted_by\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.723Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 4 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.724Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"coexists_with\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.724Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.736Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"negatively_regulates\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.736Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.737Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"negatively_regulated_by\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.737Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.737Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"disrupts\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.737Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.749Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"physically_interacts_with\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.749Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.750Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"positively_regulates\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.750Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.750Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"positively_regulated_by\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.750Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.762Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"related_to\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.763Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 18 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.763Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"prevented_by\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.763Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 1 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.764Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/semmed/query\",\"params\":{\"fields\":\"treated_by\"},\"data\":\"q=C0282687&scopes=umls\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.765Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 14 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.765Z",
            "level": "DEBUG",
            "message": "call-apis: Total number of results returned for this query is 88",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.974Z",
            "level": "DEBUG",
            "message": "call-apis: Query completes",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.978Z",
            "level": "DEBUG",
            "message": "REDIS cache is not enabled.",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:01.997Z",
            "level": "DEBUG",
            "message": "BTE found 20 smartapi edges corresponding to e02. These smartaip edges comes from 7 unique APIs. They are OpenTarget API,MyChem.info API,SEMMED Gene API,BioThings DGIdb API,Text Mining Targeted Association API,Text Mining CO-OCCURRENCE API,Drug Response KP API",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.041Z",
            "level": "DEBUG",
            "message": "BTE found 7 bte edges for this batch.",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.041Z",
            "level": "DEBUG",
            "message": "call-apis: Resolving ID feature is turned on",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.041Z",
            "level": "DEBUG",
            "message": "call-apis: Number of BTE Edges received is 7",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.102Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/text_mining_co_occurrence_kp/query\",\"params\":{\"fields\":\"subject,association\",\"q\":\"object.NCBIGene:\\\"116534309\\\" AND subject.type:ChemicalSubstance\",\"size\":1000},\"method\":\"get\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.102Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.103Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/text_mining_co_occurrence_kp/query\",\"params\":{\"fields\":\"object,association\",\"q\":\"subject.NCBIGene:\\\"116534309\\\" AND object.type:ChemicalSubstance\",\"size\":1000},\"method\":\"get\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.103Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.104Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/dgidb/query\",\"params\":{\"fields\":\"object.CHEMBL_COMPOUND,association.provided_by,association.pubmed\",\"size\":1000},\"data\":\"q=116534309&scopes=subject.NCBIGene\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.104Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.104Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://biothings.ncats.io/drug_response_kp/query\",\"params\":{\"fields\":\"association.context.disease.mondo,object.PUBCHEM,association.effect_size,association.pvalue\",\"q\":\"subject.NCBIGene:116534309 AND association.effect_size:<0 AND association.pvalue:<0.05\",\"size\":\"1000\",\"sort\":\"association.pvalue\"},\"method\":\"get\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.104Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.109Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://mychem.info/v1/query\",\"params\":{\"fields\":\"chembl.molecule_chembl_id\",\"size\":\"250\"},\"data\":\"q=CD4&scopes=drugcentral.bioactivity.uniprot.gene_symbol\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.109Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.110Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://mychem.info/v1/query\",\"params\":{\"fields\":\"drugbank.id\",\"size\":\"250\"},\"data\":\"q=CD4&scopes=drugbank.targets.gene_name\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.110Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 3 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.112Z",
            "level": "DEBUG",
            "message": "call-apis: Succesfully made the following query: {\"url\":\"https://mychem.info/v1/query\",\"params\":{\"fields\":\"drugbank.id\",\"size\":\"250\"},\"data\":\"q=CD4&scopes=drugbank.enzymes.gene_name\",\"method\":\"post\",\"timeout\":50000}",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.112Z",
            "level": "DEBUG",
            "message": "call-apis: After transformation, BTE is able to retrieve 0 hits!",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.112Z",
            "level": "DEBUG",
            "message": "call-apis: Total number of results returned for this query is 3",
            "code": null
        },
        {
            "timestamp": "2021-03-15T22:54:02.181Z",
            "level": "DEBUG",
            "message": "call-apis: Query completes",
            "code": null
        }
    ]
}

Making a branched query

const handler = require("@biothings-explorer/query_graph_handler");
const queryHandler = new handler.TRAPIQueryHandler();
const branchedQuery = {
    "workflow": [
        {"id": "lookup"}
    ],
    "message": {
        "query_graph": {
            "nodes": {
                "n0": {
                    "categories": ["biolink:Disease"],
                    "ids": ["MONDO:0005737"]
                },
                "n1": {
                    "categories": ["biolink:Gene"]
                },
                "n2": {
                    "categories": ["biolink:SmallMolecule"]
                }
            },
            "edges": {
                "e01": {
                    "subject": "n0",
                    "object": "n1"
                },
                "e02": {
                    "subject": "n0",
                    "object": "n2"
                }
            }
        }
    }
}
queryHandler.setQueryGraph(branchedQuery);
await queryHandler.query();
console.log(queryHandler.getResponse())
Example Result
{
    "workflow": [
        {"id": "lookup"}
    ],
    "message": {
        "query_graph": {
            "nodes": {
                "n0": {
                    "category": "biolink:Disease",
                    "id": "MONDO:0005737"
                },
                "n1": {
                    "category": "biolink:Gene"
                },
                "n2": {
                    "category": "biolink:ChemicalSubstance"
                }
            },
            "edges": {
                "e01": {
                    "subject": "n0",
                    "object": "n1"
                },
                "e02": {
                    "subject": "n0",
                    "object": "n2"
                }
            }
        },
        "knowledge_graph": {
            "nodes": {
                "MONDO:0005737": {
                    "category": "biolink:Disease",
                    "name": "Ebola hemorrhagic fever",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "MONDO:0005737",
                                "DOID:4325",
                                "UMLS:C0282687",
                                "name:Ebola hemorrhagic fever",
                                "MESH:D019142",
                                "EFO:0007243",
                                "ORPHANET:319218",
                                "GARD:2035"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:116534309": {
                    "category": "biolink:Gene",
                    "name": "CD4",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:116534309",
                                "name:CD4 molecule",
                                "SYMBOL:CD4"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:539109": {
                    "category": "biolink:Gene",
                    "name": "MMP11",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:539109",
                                "name:matrix metallopeptidase 11",
                                "SYMBOL:MMP11",
                                "ENSEMBL:ENSBTAG00000006108"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:102448557": {
                    "category": "biolink:Gene",
                    "name": "GTPBP1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:102448557",
                                "name:GTP binding protein 1",
                                "SYMBOL:GTPBP1",
                                "ENSEMBL:ENSPSIG00000004300"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:103074707": {
                    "category": "biolink:Gene",
                    "name": "CCL2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:103074707",
                                "name:C-C motif chemokine ligand 2",
                                "SYMBOL:CCL2"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:ENSSPUG00000015633": {
                    "category": "biolink:Gene",
                    "name": "MAPRE3",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:microtubule associated protein RP/EB family member 3",
                                "SYMBOL:MAPRE3",
                                "ENSEMBL:ENSSPUG00000015633"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:115865406": {
                    "category": "biolink:Gene",
                    "name": "BST2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:115865406",
                                "name:bone marrow stromal cell antigen 2",
                                "SYMBOL:BST2"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:110132571": {
                    "category": "biolink:Gene",
                    "name": "IL1B",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:110132571",
                                "name:interleukin 1 beta",
                                "SYMBOL:IL1B"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101571570": {
                    "category": "biolink:Gene",
                    "name": "Ifih1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101571570",
                                "name:interferon induced with helicase C domain 1",
                                "SYMBOL:Ifih1",
                                "ENSEMBL:ENSODEG00000013586"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:ENSSMAG00000017984": {
                    "category": "biolink:Gene",
                    "name": "npc1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:Niemann-Pick disease, type C1",
                                "SYMBOL:npc1",
                                "ENSEMBL:ENSSMAG00000017984"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:397686": {
                    "category": "biolink:Gene",
                    "name": "IFNA1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:397686",
                                "name:interferon, alpha 1",
                                "SYMBOL:IFNA1",
                                "ENSEMBL:ENSSSCG00000050619"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:102892030": {
                    "category": "biolink:Gene",
                    "name": "ALB",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:102892030",
                                "name:albumin",
                                "SYMBOL:ALB"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:104045425": {
                    "category": "biolink:Gene",
                    "name": "HDX",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:104045425",
                                "name:highly divergent homeobox",
                                "SYMBOL:HDX"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:110137949": {
                    "category": "biolink:Gene",
                    "name": "CXCL10",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:110137949",
                                "name:C-X-C motif chemokine ligand 10",
                                "SYMBOL:CXCL10"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:105822820": {
                    "category": "biolink:Gene",
                    "name": "CXCL8",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:105822820",
                                "name:C-X-C motif chemokine ligand 8",
                                "SYMBOL:CXCL8",
                                "ENSEMBL:ENSPCOG00000024593"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:116479423": {
                    "category": "biolink:Gene",
                    "name": "CLEC4M",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:116479423",
                                "name:C-type lectin domain family 4 member M",
                                "SYMBOL:CLEC4M"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:103814882": {
                    "category": "biolink:Gene",
                    "name": "F3",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:103814882",
                                "name:coagulation factor III, tissue factor",
                                "SYMBOL:F3",
                                "ENSEMBL:ENSSCAG00000012591"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101142722": {
                    "category": "biolink:Gene",
                    "name": "KPNA1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101142722",
                                "name:karyopherin subunit alpha 1",
                                "SYMBOL:KPNA1"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:104673720": {
                    "category": "biolink:Gene",
                    "name": "CTSL",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:104673720",
                                "name:cathepsin L",
                                "SYMBOL:CTSL",
                                "ENSEMBL:ENSRROG00000038398"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:116543050": {
                    "category": "biolink:Gene",
                    "name": "CTSB",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:116543050",
                                "name:cathepsin B",
                                "SYMBOL:CTSB"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:29798": {
                    "category": "biolink:Gene",
                    "name": "C2orf27A",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:29798",
                                "name:chromosome 2 open reading frame 27A",
                                "SYMBOL:C2orf27A",
                                "UMLS:C2681192",
                                "HGNC:25077",
                                "UniProtKB:P0DPF5"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:118012204": {
                    "category": "biolink:Gene",
                    "name": "STAT1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:118012204",
                                "name:signal transducer and activator of transcription 1",
                                "SYMBOL:STAT1"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101937382": {
                    "category": "biolink:Gene",
                    "name": "KPNA5",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101937382",
                                "name:karyopherin subunit alpha 5",
                                "SYMBOL:KPNA5"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:ENSNVIG00000024389": {
                    "category": "biolink:Gene",
                    "name": "IFIT2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:interferon induced protein with tetratricopeptide repeats 2",
                                "SYMBOL:IFIT2",
                                "ENSEMBL:ENSNVIG00000024389"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:104395366": {
                    "category": "biolink:Gene",
                    "name": "THBD",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:104395366",
                                "name:thrombomodulin",
                                "SYMBOL:THBD"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:100731608": {
                    "category": "biolink:Gene",
                    "name": "Isg15",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:100731608",
                                "name:ISG15 ubiquitin like modifier",
                                "SYMBOL:Isg15"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:108529797": {
                    "category": "biolink:Gene",
                    "name": "DDX58",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:108529797",
                                "name:DExD/H-box helicase 58",
                                "SYMBOL:DDX58",
                                "ENSEMBL:ENSRBIG00000040257"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:106971145": {
                    "category": "biolink:Gene",
                    "name": "IFNB1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:106971145",
                                "name:interferon beta 1",
                                "SYMBOL:IFNB1"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:ENSCJAG00000047270": {
                    "category": "biolink:Gene",
                    "name": "GP2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:glycoprotein 2",
                                "SYMBOL:GP2",
                                "ENSEMBL:ENSCJAG00000047270"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101443464": {
                    "category": "biolink:Gene",
                    "name": "GPT",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101443464",
                                "name:glutamic--pyruvic transaminase",
                                "SYMBOL:GPT"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:102387082": {
                    "category": "biolink:Gene",
                    "name": "IRF7",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:102387082",
                                "name:interferon regulatory factor 7",
                                "SYMBOL:IRF7"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:109055884": {
                    "category": "biolink:Gene",
                    "name": "il6",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:109055884",
                                "name:interleukin 6 (interferon, beta 2)",
                                "SYMBOL:il6",
                                "ENSEMBL:ENSCCRG00000034667"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:ENSSBOG00000011322": {
                    "category": "biolink:Gene",
                    "name": "CD8A",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:CD8a molecule",
                                "SYMBOL:CD8A",
                                "ENSEMBL:ENSSBOG00000011322"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:117759282": {
                    "category": "biolink:Gene",
                    "name": "ace2",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:117759282",
                                "name:angiotensin I converting enzyme 2",
                                "SYMBOL:ace2"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:103562469": {
                    "category": "biolink:Gene",
                    "name": "TNF",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:103562469",
                                "name:tumor necrosis factor",
                                "SYMBOL:TNF"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:112648300": {
                    "category": "biolink:Gene",
                    "name": "IL10",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:112648300",
                                "name:interleukin 10",
                                "SYMBOL:IL10",
                                "ENSEMBL:ENSCAFG00020012434"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:106483620": {
                    "category": "biolink:Gene",
                    "name": "ERVW-1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:106483620",
                                "name:endogenous retrovirus group W member 1, envelope",
                                "SYMBOL:ERVW-1"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:118335909": {
                    "category": "biolink:Gene",
                    "name": "irf3",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:118335909",
                                "name:interferon regulatory factor 3",
                                "SYMBOL:irf3"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101674197": {
                    "category": "biolink:Gene",
                    "name": "CCL5",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101674197",
                                "name:C-C motif chemokine ligand 5",
                                "SYMBOL:CCL5"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:103089296": {
                    "category": "biolink:Gene",
                    "name": "CCL3",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:103089296",
                                "name:C-C motif chemokine ligand 3",
                                "SYMBOL:CCL3"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "ENSEMBL:MGP_SPRETEiJ_G0017727": {
                    "category": "biolink:Gene",
                    "name": "Ccl4",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "name:chemokine (C-C motif) ligand 4",
                                "SYMBOL:Ccl4",
                                "ENSEMBL:MGP_SPRETEiJ_G0017727"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:101998427": {
                    "category": "biolink:Gene",
                    "name": "Furin",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:101998427",
                                "name:furin, paired basic amino acid cleaving enzyme",
                                "SYMBOL:Furin",
                                "ENSEMBL:ENSMOCG00000010449"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:574217": {
                    "category": "biolink:Gene",
                    "name": "CCL4L1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:574217",
                                "name:chemokine (C-C motif) ligand 4-like 1",
                                "SYMBOL:CCL4L1",
                                "UniProtKB:Q8HYQ2",
                                "ENSEMBL:ENSMMUG00000020102"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1707151": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1707151",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1707151"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1707163": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1707163",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1707163"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:3601": {
                    "category": "biolink:Gene",
                    "name": "IL15RA",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:3601",
                                "name:interleukin 15 receptor subunit alpha",
                                "SYMBOL:IL15RA",
                                "UMLS:C1416387",
                                "HGNC:5978",
                                "UniProtKB:Q13261",
                                "ENSEMBL:ENSG00000134470",
                                "OMIM:601070"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:5788": {
                    "category": "biolink:Gene",
                    "name": "PTPRC",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:5788",
                                "name:protein tyrosine phosphatase receptor type C",
                                "SYMBOL:PTPRC",
                                "UMLS:C1335285",
                                "HGNC:9666",
                                "UniProtKB:P08575",
                                "ENSEMBL:ENSG00000081237",
                                "ENSEMBL:ENSG00000262418",
                                "OMIM:151460"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:8030": {
                    "category": "biolink:Gene",
                    "name": "CCDC6",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:8030",
                                "name:coiled-coil domain containing 6",
                                "SYMBOL:CCDC6",
                                "UMLS:C1425774",
                                "HGNC:18782",
                                "UniProtKB:Q16204",
                                "ENSEMBL:ENSG00000108091",
                                "OMIM:601985"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:920": {
                    "category": "biolink:Gene",
                    "name": "CD4",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:920",
                                "name:CD4 molecule",
                                "SYMBOL:CD4",
                                "UMLS:C1332714",
                                "HGNC:1678",
                                "UniProtKB:P01730",
                                "ENSEMBL:ENSG00000010610",
                                "OMIM:186940"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:1514": {
                    "category": "biolink:Gene",
                    "name": "CTSL",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:1514",
                                "name:cathepsin L",
                                "SYMBOL:CTSL",
                                "UMLS:C1332807",
                                "UMLS:C0054871",
                                "HGNC:2537",
                                "UniProtKB:P07711",
                                "ENSEMBL:ENSG00000135047",
                                "OMIM:116880"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1706438": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1706438",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1706438"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1367471": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1367471",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1367471"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "MESH:C480354": {
                    "category": "biolink:ChemicalSubstance",
                    "name": "BH30sucMan",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1433528",
                                "MESH:C480354",
                                "name:BH30sucMan"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "CHEBI:134722": {
                    "category": "biolink:ChemicalSubstance",
                    "name": "FAVIPIRAVIR",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "CHEMBL.COMPOUND:CHEMBL221722",
                                "DRUGBANK:DB12466",
                                "PUBCHEM.COMPOUND:492405",
                                "CHEBI:134722",
                                "UMLS:C1138226",
                                "MESH:C462182",
                                "UNII:EW5GL2X7E0",
                                "INCHIKEY:ZCGNOVWYSGBHAU-UHFFFAOYSA-N",
                                "INCHI:InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)",
                                "name:FAVIPIRAVIR",
                                "name:Favipiravir",
                                "name:favipiravir"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "MESH:C517546": {
                    "category": "biolink:ChemicalSubstance",
                    "name": "immucillin A",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1870231",
                                "MESH:C517546",
                                "name:immucillin A",
                                "name:immucillin-A"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "MESH:C487484": {
                    "category": "biolink:ChemicalSubstance",
                    "name": "K11777",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C1456738",
                                "MESH:C487484",
                                "name:K11777"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "MESH:C000606551": {
                    "category": "biolink:ChemicalSubstance",
                    "name": "GS-5734",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "UMLS:C4279131",
                                "MESH:C000606551",
                                "name:GS-5734"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "CHEBI:29687": {
                    "category": "biolink:ChemicalSubstance",
                    "name": "TEICOPLANIN",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "CHEMBL.COMPOUND:CHEMBL2367892",
                                "DRUGBANK:DB06149",
                                "PUBCHEM.COMPOUND:73348316",
                                "PUBCHEM.COMPOUND:16131923",
                                "CHEBI:29687",
                                "UMLS:C0145106",
                                "MESH:D017334",
                                "UNII:4U3D3YY81M",
                                "INCHI:InChI=1S/C80H81Cl2N9O33/c1-26(95)84-59-65(104)62(101)50(23-92)120-78(59)123-69-31-6-10-45(40(82)16-31)118-49-19-33-18-48(70(49)124-79-60(85-27(2)96)66(105)63(102)51(24-93)121-79)117-44-9-3-28(11-39(44)81)12-41-71(108)87-56(32-13-34(97)20-36(14-32)116-46-17-29(4-8-43(46)100)54(83)72(109)86-41)74(111)89-57(33)75(112)88-55-30-5-7-42(99)37(15-30)53-38(58(77(114)115)90-76(113)61(69)91-73(55)110)21-35(98)22-47(53)119-80-68(107)67(106)64(103)52(25-94)122-80/h3-11,13-22,41,50-52,54-69,78-80,92-94,97-107H,12,23-25,83H2,1-2H3,(H,84,95)(H,85,96)(H,86,109)(H,87,108)(H,88,112)(H,89,111)(H,90,113)(H,91,110)(H,114,115)/t41-,50+,51+,52-,54-,55-,56+,57-,58+,59+,60+,61+,62-,63-,64-,65-,66-,67-,68+,69-,78+,79+,80+/m1/s1",
                                "name:TEICOPLANIN"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "NCBIGene:3439": {
                    "category": "biolink:Gene",
                    "name": "IFNA1",
                    "attributes": [
                        {
                            "name": "equivalent_identifiers",
                            "value": [
                                "NCBIGene:3439",
                                "name:interferon alpha 1",
                                "SYMBOL:IFNA1",
                                "UMLS:C1415900",
                                "HGNC:5417",
                                "UniProtKB:P01562",
                                "ENSEMBL:ENSG00000197919",
                                "OMIM:147660"
                            ],
                            "type": "biolink:id"
                        }
                    ]
                },
                "UMLS:C1708411": {
                    "category": "biolink:Gene",
                    "name": "UMLS:C1708411",
                    "attributes": [
                        {
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                                "INCHIKEY:BDHFUVZGWQCTTF-UHFFFAOYSA-M",
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                "CHEBI:53116": {
                    "category": "biolink:ChemicalSubstance",
                    "name": "CMP 3'-end residue",
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                            "value": [
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                                "name:CMP 3'-end residue"
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                "CHEBI:31577": {
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                "CHEBI:22256": {
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                    "name": "CHEBI:35274",
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                "CHEBI:50300": {
                    "category": "biolink:ChemicalSubstance",
                    "name": "thymidine 5'-monophosphate residue",
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                                "UNII:CPD4NFA903",
                                "INCHIKEY:XAGFODPZIPBFFR-UHFFFAOYSA-N",
                                "INCHI:InChI=1S/Al",
                                "KEGG:C06264",
                                "name:Aluminium",
                                "name:Aluminum",
                                "name:ALUMINUM",
                           

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